Platelet rich plasma (PRP) is an autologous blood concentrate that has gained popularity among physicians and patients for the treatment of a variety of orthopedic conditions and injuries. The basis for its use involves the local delivery of growth factors, modulators of inflammation, and molecules that enhance the adhesion of cells.
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Investigators at Washington University School of Medicine in St. Louis, Shriners Hospital for Children in St. Louis, Duke University, and Cytex Therapeutics Inc. have developed a technology using so called SMART cells (Stem cells Modified for Autonomous Regenerative Therapy) that will develop into cartilage cells and at the same time produce a biologic anti-inflammatory drug, which will protect joints from the damage that results from chronic inflammation. Using a gene-editing tool known as CRISPR, the investigators remove a specific gene that is involved with inflammation and replace it with a gene that will release a biologic drug that fights inflammation.
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Enjoy your daily activities knowing you are in control of your arthritis
